Down-regulation of p27 by Two Mechanisms, Ubiquitin-mediated Degradation and Proteolytic Processing
نویسندگان
چکیده
منابع مشابه
Down-regulation of Delta by proteolytic processing
Notch signaling regulates cell fate decisions during development through local cell interactions. Signaling is triggered by the interaction of the Notch receptor with its transmembrane ligands expressed on adjacent cells. Recent studies suggest that Delta is cleaved to release an extracellular fragment, DlEC, by a mechanism that involves the activity of the metalloprotease Kuzbanian; however, t...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1999
ISSN: 0021-9258
DOI: 10.1074/jbc.274.20.13886